HERV-FRD (ERVFRD-1) Rabbit Polyclonal Antibody

SKU TA335112

Rabbit polyclonal Anti-HERV-FRD Antibody

Product Data

• Application: WB
• Recommended Dilution: WB
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-HERV-FRD antibody: synthetic peptide directed towards the N terminal of human HERV-FRD. Synthetic peptide located within the following region: TGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPNLKG
• Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 55 kDa
• Gene Name: endogenous retrovirus group FRD member 1
• Database Link:
  NP_997465
  P60508
• Background: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors.
• Synonyms: envFRD; ERVFRDE1; FRD; GLLL6191; HERV-FRD; HERV-W; UNQ6191
• Note: Immunogen Sequence Homology: Human: 100%

Reference Data

• Protein Families: Transmembrane