HERV-FRD (ERVFRD-1) Rabbit Polyclonal Antibody

CAT#: TA335112

Rabbit polyclonal Anti-HERV-FRD Antibody

Product Images

WB Suggested Anti-HERV-FRD Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HT1080 cell lysate

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-HERV-FRD antibody: synthetic peptide directed towards the N terminal of human HERV-FRD. Synthetic peptide located within the following region: TGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPNLKG
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: endogenous retrovirus group FRD member 1
• Database Link:
  NP_997465
  Entrez Gene 405754 Human
  UniProt ID P60508
• Background: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors.
• Synonyms: envFRD; ERVFRDE1; FRD; GLLL6191; HERV-FRD; HERV-W; UNQ6191
• Note: Immunogen Sequence Homology: Human: 100%

Reference Data

• Protein Families: Transmembrane