CORD2 (CRX) Rabbit Polyclonal Antibody

CAT#: TA332861

Rabbit anti-CRX Polyclonal Antibody

Product Images

Western blot analysis of extracts of Mouse eye cell line, using CRX antibody.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CRX
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: cone-rod homeobox
• Database Link:
  NP_000545
  Entrez Gene 12951 Mouse
  UniProt ID O43186
• Background: The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
• Synonyms: CORD2; CRD; LCA7; OTX3

Reference Data

• Protein Families: Druggable Genome, Transcription Factors