N WASP(WASL) Rabbit Polyclonal Antibody
Rabbit anti-WASL Polyclonal Antibody
Product Datasheet for 'TA332562'
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|Applications||WB, IHC, IF|
|Recommend Dilution||WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Recombinant protein of human WASL|
|Formulation||Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Predicted Protein Size||505|
|Gene Name||Wiskott-Aldrich syndrome like|
|Background||This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.|
|Protein Families||Druggable Genome|
|Protein Pathways||Chemokine signaling pathway, Adherens junction, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection|