ATP5F1C Goat Polyclonal Antibody

SKU TA329078

ATP5F1C Goat Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 0.01-0.03ug/ml ; ELISA: 1:128,000 ; IHC: Paraffin embedded Human Heart. Recommended concentration: 5µg/ml
• Reactivity: Cow), Dog, Human, Rat (Expected from sequence similarity: Mouse
• Antibody Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-TLTFNRTRQAVITKE, from C terminus of the protein sequence according to NP_005165.1 and NP_001001973.1.
• Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
• Database Link:
  NP_001001973
  P36542
• Background: This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. [provided by RefSeq, Jul 2008]
• Synonyms: ATP5; ATP5C

Reference Data

• Protein Pathways: Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease