Rorc Mouse Monoclonal Antibody [Clone ID: 4F3-3C8-2B7]

SKU TA328098

Mouse Monoclonal anti-ROR? Antibody

Product Data

• Clone Name: 4F3-3C8-2B7
• Application: WB
• Recommended Dilution: WB
• Reactivity: Human, Mouse (weak)
• Antibody Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Human ROR?-GST recombinant protein
• Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: RAR-related orphan receptor gamma
• Database Link:
  NP_035411
  P51450
• Background: RORγ (Retinoid-related orphan receptor gamma) belongs to the nuclear hormone receptor family, NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. RORγ has two isoforms: γ1 and γ2 (also referred to as RORγt). The RORγt differs from the RORγ1 isoform in that it lacks the amino terminus of RORγ1. RORγ1 contains 516 amino acids and RORγt contains 495 amino acids. RORγ1 has a molecular weight of approximately 58 kD. RORγ1 is highly expressed in thymus, kidney, liver, muscle, and brown fat but not in white fat tissue. RORγt is specifically expressed in only two cell populations, DP thymocytes and lymphoid tissue inducers (LTi). RORγ plays a critical role in control apoptosis during thymopoiesis and T cell homeostasis. RORγ is to regulate TCRα repertoire by virtue of its positive regulatory role on Bcl-x expression. RORγ is essential for lymph nodes and Peyers patches development.
• Synonyms: MGC129539; NR1F3; RORG; RZR-GAMMA; RZRG; TOR

Reference Data