H3FT (HIST3H3) Rabbit Polyclonal Antibody
Product Data | |
Application | ChIP, ChIP-seq, Dot, ELISA, ICC/IF, IHC, IP, WB |
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Recommended Dilution | WB,1:500 - 1:1000 DB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP,5μg antibody for 5μg-10μg of Chromatin ChIP-seq,1:20 - 1:100 |
Reactivity | Human, Mouse, Other (Wide Range), Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Buffer | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 16kDa |
Gene Name | histone cluster 3, H3 |
Database Link | |
Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
Synonyms | g; H3; H3.4; H3FT; H3t |
Reference Data | |
Protein Pathways | Systemic lupus erythematosus |
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