XRCC3 Rabbit Polyclonal Antibody

CAT#: TA327290

Rabbit anti-XRCC3 Polyclonal Antibody

Product Images

Western blot analysis of extracts of HL60 cell lines, using XRCC3 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human XRCC3
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 3
• Database Link:
  NP_005423
  Entrez Gene 7517 Human
  UniProt ID O43542
• Background: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
• Synonyms: CMM6

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination