RPGR Rabbit Polyclonal Antibody

CAT#: TA327197

RPGR Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using RPGR antibody.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human RPGR
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: retinitis pigmentosa GTPase regulator
• Database Link:
  NP_000319
  Entrez Gene 19893 MouseEntrez Gene 367733 RatEntrez Gene 6103 Human
  UniProt ID Q92834
• Background: This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq, Dec 2008]
• Synonyms: COD1; CORDX1; CRD; orf15; PCDX; RP3; RP15; XLRP3

Reference Data

• Protein Families: Druggable Genome