SHMT2 Rabbit Polyclonal Antibody
Product Data | |
Application | ELISA, IHC, WB |
---|---|
Recommended Dilution | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Buffer | Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 56kDa |
Gene Name | serine hydroxymethyltransferase 2 |
Database Link | |
Background | This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. |
Synonyms | GLYA; HEL-S-51e; SHMT |
Reference Data | |
Protein Pathways | Cyanoamino acid metabolism, Glycine, Metabolic pathways, Methane metabolism, One carbon pool by folate, serine and threonine metabolism |
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