SHMT2 Rabbit Polyclonal Antibody

SKU
TA327002
Rabbit anti-SHMT2 Polyclonal Antibody
$475.00
3 Weeks*
Specifications
Product Data
Application ELISA, IHC, WB
Recommended Dilution WB,1:500 - 1:2000
IHC-P,1:50 - 1:200
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Buffer Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 56kDa
Gene Name serine hydroxymethyltransferase 2
Database Link
Background This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.
Synonyms GLYA; HEL-S-51e; SHMT
Reference Data
Protein Pathways Cyanoamino acid metabolism, Glycine, Metabolic pathways, Methane metabolism, One carbon pool by folate, serine and threonine metabolism
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.