GLIPR1 Rabbit Polyclonal Antibody
Product Data | |
Application | IF, WB |
---|---|
Recommended Dilution | WB: 1 - 2 ug/mL, IF: 5 ug/mL |
Reactivity | Human, Mouse |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | GLIPR1 antibody was raised against an 18 amino acid peptide near the center of human GLIPR1. |
Buffer | GLIPR1 antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | GLIPR1 antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | Predicted: 29 kDa; Observed: 24 kDa |
Gene Name | GLI pathogenesis related 1 |
Database Link | |
Background | The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer (2). The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary (3). |
Synonyms | CRISP7; GLIPR; RTVP1 |
Reference Data | |
Protein Families | Transmembrane |
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