C11orf2 (VPS51) Rabbit Polyclonal Antibody

CAT#: TA326632

Rabbit Polyclonal Fat Free Antibody

Product Images

Western blot analysis of Fat Free in mouse brain tissue lysate with Fat Free antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fat Free antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human Fat Free.
• Formulation: Fat Free Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Fat Free Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 86 kDa
• Gene Name: VPS51, GARP complex subunit
• Database Link:
  NP_037397
  Entrez Gene 68505 MouseEntrez Gene 100361915 RatEntrez Gene 738 Human
  UniProt ID Q9UID3
• Background: Fat Free Antibody: Fat Free, also known as ANG2, was identified though a yeast two-hybrid screen using VP53. It is thought to be a structural and functional homolog of the yeast protein VPS51, a protein that together with VPS52, VPS53, and VPS54 form the Golgi-associated retrograde protein (GARP) complex that mediates the tethering and fusion of endosome-derived transport carriers to the trans-Golgi network (TGN). Similar to depletion of any of the VPS52, VPS53, or VPS54, depletion of Fat Free using RNAi impairs protein retrieval to the TGN indicating that Fat Free is missing component of the GARP complex in most eukaryotes.
• Synonyms: ANG2; ANG3; C11orf2; C11orf3; FFR