Bassoon (BSN) Rabbit Polyclonal Antibody

SKU TA326448

Rabbit Polyclonal Anti-Bassoon Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1:1000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
• Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: bassoon presynaptic cytomatrix protein
• Database Link:
  NP_003449
  Q9UPA5
• Background: Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntingtin, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to colocalize with GABA (A) and glutamate (GluR1) receptors.
• Synonyms: ZNF231
• Note: Detects ~420kDa, corresponding to the molecular mass of Bassoon. Multiple isoforms can be detected.

Reference Data