PSMD5 Rabbit Polyclonal Antibody

SKU TA324262

Anti-PSMD5 Rabbit Polyclonal Antibody

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1:1000-2000, WB: 1:200-1000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 2-250 amino acids of human proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 56 kDa
• Gene Name: proteasome 26S subunit, non-ATPase 5
• Database Link:
  NP_001257356
  Q16401
• Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes; a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base; which contains 6 ATPase subunits and 2 non-ATPase subunits; and a lid; which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.?
• Synonyms: S5B

Reference Data