Calpain 1 (CAPN1) Rabbit Polyclonal Antibody

SKU TA324116

Anti-CAPN1 Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1000-5000; WB positive control: K562, Jurkat and Hela cell lysates; IHC: 50-200; Positive control: Human tonsil; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 543-713 amino acids of Human Calpain-1 catalytic subunit
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 82 kDa
• Gene Name: calpain 1
• Database Link:
  NP_001185797
  P07384
• Background: The calpains; calcium-activated neutral proteases; are nonlysosomal; intracellular cysteine proteases. The mammalian calpains include ubiquitous; stomach-specific; and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large; catalytic subunits associated with a common small; regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme; calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
• Synonyms: CANP; CANP1; CANPL1; muCANP; muCL; SPG76

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Alzheimer's disease, Apoptosis