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COX11 Rabbit Polyclonal Antibody

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SKU
TA323960
Anti-COX11 Rabbit Polyclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $305.00
2 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00
LY418029 Transient overexpression lysate of COX11 homolog, cytochrome c oxidase assembly protein (yeast) (COX11), nuclear gene encoding mitochondrial protein, transcript variant 1 (as WB positive control) 100 ug
$436.00

View other "COX11 or NM_001162861" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 1000-5000
WB positive control: Mouse brain tissue
IHC: 25-100
Positive control: Human stomach cancer
Predicted cell location: Cytoplasm, Cell membrane
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 115-276 amino acids of human cytochrome c oxidase assembly homolog 11 (yeast)
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 31 kDa
Gene Name COX11 cytochrome c oxidase copper chaperone
Database Link
Background Cytochrome c oxidase (COX); the terminal component of the mitochondrial respiratory chain; catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer; and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit; but may be a heme A biosynthetic enzyme involved in COX formation; according to the yeast mutant studies. However; the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis; but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.?
Synonyms COX11P
Reference Data
Protein Categories Membrane Proteins
Protein Families Transmembrane
Protein Pathways Metabolic pathways, Oxidative phosphorylation
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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