SLC22A17 Rabbit Polyclonal Antibody

CAT#: TA322261

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Anti-SLC22A17 Rabbit Polyclonal Antibody

 Product Datasheet for 'TA322261'

USD 335.00

In Stock

    • 100 ul

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Product Data
Applications IHC, WB
Recommend Dilution ELISA: 1:2000-5000, WB: 1:500-2000, IHC: 1:25-100
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 511-524 amino acids of human solute carrier family 22, member 17
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 1.2mg/ml
Purification Antigen affinity purification
Predicted Protein Size 56 kDa
Gene Name solute carrier family 22 member 17
Background Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3); followed by internalization of holo-24p3 and release of iron; thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3); followed by internalization of apo-24p3 and its association with an intracellular siderophore; leading to iron chelation and iron transfer to the extracellular medium; thereby reducing intracellular iron concentration and resulting in apoptosis.
Reference Data
Protein Families Druggable Genome, Transmembrane
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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