Tropomyosin 2 (TPM2) Rabbit Polyclonal Antibody

SKU TA321952

Anti-TPM2 Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Human cervical cancer tissue; IHC: 50-200; Positive control: Human esophagus cancer; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 188-207 amino acids of Human tropomyosin 2 (beta)
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 33 kDa
• Gene Name: tropomyosin 2 (beta)
• Database Link:
  NP_998839
  P07951
• Background: This gene encodes beta-tropomyosin; a member of the actin filament binding protein family; and mainly expressed in slow; type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins; and cause cap disease; nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. TPM2 has been shown to interact with RRAD; PDLIM7 and TPM1.
• Synonyms: AMCD1; DA1; DA2B; HEL-S-273; NEM4; TMSB

Reference Data

• Protein Pathways: Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)