14-3-3 epsilon (YWHAE) Rabbit Polyclonal Antibody

CAT#: TA321782

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Anti-YWHAE Rabbit Polyclonal Antibody


Product Datasheet for 'TA321782'


USD 345.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1:2000-10000, WB: 1:1000-5000, IHC: 1:100-300
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 70-84 amino acids of Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 4.4mg/ml
Purification Antigen affinity purification
Predicted Protein Size 29 kDa
Gene Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
Background This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals; and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases; RAF1 and IRS1 proteins; suggesting its role in diverse biochemical activities related to signal transduction; such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants; one protein-coding and the other non-protein-coding; have been found for this gene.?
Synonyms 14-3-3E; HEL2; KCIP-1; MDCR; MDS
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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