CDC42 Rabbit Polyclonal Antibody

CAT#: TA321400

Reviews ()
Write a review

Anti-Cdc42/Rho/Rac Rabbit Polyclonal Antibody



USD 345.00


Availability*
In Stock

Size
    • 100 ul


Product images

Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1:1000-2000, WB: 1:200-1000
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 57-71 amino acids of Human Cell division cycle 42
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 23 kDa
Gene Name cell division cycle 42
Background The protein encoded by this gene is a small GTPase of the Rho-subfamily; which regulates signaling pathways that control diverse cellular functions including cell morphology; migration; endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42; and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP); which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
Synonyms CDC42Hs; G25K; TKS
Reference Data
Protein Families Druggable Genome
Protein Pathways Adherens junction, Axon guidance, Chemokine signaling pathway, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Fc gamma R-mediated phagocytosis, Focal adhesion, GnRH signaling pathway, Leukocyte transendothelial migration, MAPK signaling pathway, Neurotrophin signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway, Tight junction, VEGF signaling pathway
Other products for "CDC42"
Frequently bought together (3)
Recombinant protein of human cell division cycle 42 (GTP binding protein, 25kDa) (CDC42), transcript variant 1
    • 20 ug

USD 748.00


Transient overexpression lysate of cell division cycle 42 (GTP binding protein, 25kDa) (CDC42), transcript variant 1
    • 100 ug

USD 325.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 159.00

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Antibody Performance Guarantee banner
ANTIBODY VALIDATION 101
Clone ID reveals the Source of Monoclonal Antibodies