Bak (BAK1) Rabbit Polyclonal Antibody

CAT#: TA321299

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Anti-BAK1 rabbit polyclonal antibody



USD 380.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1000-5000
WB positive control: Hela, A431, 293T and Jurkat cells
IHC: 50-200
Positive control: Human esophagus cancer
Predicted cell location: Cytoplasm
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 4-187 amino acids of human BCL2-antagonist/killer 1
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 23 kDa
Gene Name BCL2 antagonist/killer 1
Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.?
Synonyms BAK; BAK-LIKE; BCL2L7; CDN1
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transmembrane
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