Snf1lk (SIK1) Rabbit Polyclonal Antibody

CAT#: TA320117

Rabbit Polyclonal SIK1 Antibody

Product Images

Western blot analysis of SIK1 in human small intestine tissue lysate with SIK1 antibody at 1 ug/mL.

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  Immunohistochemistry of SIK1 in human small intestine tissue with SIK1 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SIK1 antibody was raised against an 18 amino acid synthetic peptide near the center of human SIK1.
• Formulation: SIK1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SIK1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: salt inducible kinase 1
• Database Link:
  NP_775490
  Entrez Gene 150094 Human
  UniProt ID P57059
• Background: SIK1 Antibody: Salt-inducible kinase 1 (SIK1), also known as SNF1LK or MSK, plays a role in histone modification and G2/M cell cycle regulation. It is a 783 amino acid protein that contains one UBA domain and belongs to the Ser/Thr protein kinase family (AMPK subfamily). Localized to both the nucleus and the cytoplasm, SIK1 is a class II HDAC kinase that uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation.
• Synonyms: MSK; SIK; SNF1LK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase