Zfp219 (ZNF219) Rabbit Polyclonal Antibody

CAT#: TA319916

Rabbit Polyclonal ZFP219 Antibody

Product Images

Western blot analysis of ZFP219 in mouse brain tissue lysate with ZFP219 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of ZFP219 in mouse brain tissue with ZFP219 antibody at 5 ug/mL.

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  Immunofluorescence of ZFP219 in mouse brain tissue with ZFP219 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ZFP219 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZFP219.
• Formulation: ZFP219 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ZFP219 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: zinc finger protein 219
• Database Link:
  NP_001095142
  Entrez Gene 51222 Human
  UniProt ID Q9P2Y4
• Background: ZFP219 Antibody: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.
• Synonyms: ZFP219

Reference Data

• Protein Families: Transcription Factors