Uroplakin Ib (UPK1B) Rabbit Polyclonal Antibody

CAT#: TA319733

Rabbit Polyclonal UPK1B Antibody

Product Images

Western blot analysis of UPK1B in mouse bladder tissue lysate with UPK1B antibody at (A) 0.5 and (B) 1 ug/mL.

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  Immunohistochemistry of UPK1B in human bladder tissue with UPK1B antibody at 5 ug/mL.

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  Immunofluorescence of UPK1B in human bladder muscle tissue with UPK1B antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: UPK1B antibody was raised against a 17 amino acid synthetic peptide near the center of human UPK1B.
• Formulation: UPK1B Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: UPK1B Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: uroplakin 1B
• Database Link:
  NP_008883
  Entrez Gene 22268 MouseEntrez Gene 303924 RatEntrez Gene 7348 Human
  UniProt ID O75841
• Background: UPK1B Antibody: Uroplakin-1B (UPK1B) is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. UPK1B is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins and may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
• Synonyms: TSPAN20; UPIB; UPK1

Reference Data

• Protein Families: Transmembrane