TARC (CCL17) Rabbit Polyclonal Antibody
Product Data | |
Application | IF, IHC, WB |
---|---|
Recommended Dilution | WB: 1 - 2 ug/mL |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Rabbit polyclonal CCL17 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CCL17. |
Buffer | CCL17 Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | CCL17 Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 10 kDa |
Gene Name | C-C motif chemokine ligand 17 |
Database Link | |
Background | CCL17 Antibody: CCL17, also known as TARC, binds to chemokine receptors CCR4 and CCR8 and plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is secreted from monocyte-derived DCs and endothelial cells and is responsible for selective recruitment and migration of activated Th2 lymphocytes. CCL17 is also required for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells under inflammatory conditions. |
Synonyms | A-152E5.3; ABCD-2; SCYA17; TARC |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
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