Transmembrane 4 L6 family member 1 (TM4SF1) Rabbit Polyclonal Antibody

CAT#: TA319680

Rabbit Polyclonal TM4SF1 Antibody

Product Images

Western blot analysis of TM4SF1 in human lung tissue lysate with TM4SF1 antibody at (A) 0.5 and (B) 1ug/ml.

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  Immunohistochemistry of TM4SF1 in mouse lung tissue with TM4SF1 antibody at 5ug/ml.

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  Immunohistochemistry of TM4SF1 in mouse lung tissue with TM4SF1 antibody at 2ug/ml.

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  Immunohistochemistry of TM4SF1 in human lung tissue with TM4SF1 antibody at 5ug/ml.

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  Immunofluorescence of TM4SF1 in human lung tissue with TM4SF1 antibody at 20ug/ml.

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  Immunofluorescence of TM4SF1 in mouse lung tissue with TM4SF1 antibody at 20ug/ml.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TM4SF1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TM4SF1. The immunogen is located within the first 50 amino acids of TM4SF1.
• Formulation: TM4SF1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TM4SF1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: transmembrane 4 L six family member 1
• Database Link:
  NP_055035
  Entrez Gene 17112 MouseEntrez Gene 295061 RatEntrez Gene 4071 Human
  UniProt ID P30408
• Background: TM4SF1 Antibody: TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.
• Synonyms: H-L6; L6; M3S1; TAAL6

Reference Data

• Protein Families: Transmembrane