TSC22D3 Rabbit Polyclonal Antibody

CAT#: TA319636

Rabbit Polyclonal TSC22D3 Antibody

Product Images

Western blot analysis of TSC22D3 in human small intestine tissue lysate with TSC22D3 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of TSC22D3 in human small intestine tissue with TSC22D3 antibody at 5 ug/mL.

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  Immunofluorescence of TSC22D3 in human small intestine tissue with TSC22D3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Rabbit polyclonal TSC22D3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TSC22D3.
• Formulation: TSC22D3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TSC22D3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 22 kDa
• Gene Name: TSC22 domain family member 3
• Database Link:
  NP_932174
  Entrez Gene 1831 Human
  UniProt ID Q99576
• Background: TSC22D3 Antibody: The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-κB and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-κB. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
• Synonyms: DIP; DSIPI; GILZ; TSC-22R