Ku80(XRCC5) Rabbit Polyclonal Antibody

CAT#: TA308827

Rabbit polyclonal antibody to Ku80 (XRCC5) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))

Bulk Request/Custom Conjugation

 Product Datasheet for 'TA308827'

USD 416.00

5 Days

    • 100 ul

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Product Data
Applications WB, IHC, IF, IP
Recommend Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 315 and 593 of Ku80 (Uniprot ID#P13010)
Isotype IgG
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration 1.01mg/ml
Purification Purified by antigen-affinity chromatography.
Predicted Protein Size 83kDa
Gene Name X-ray repair complementing defective repair in Chinese hamster cells 5
Background The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
Synonyms KARP-1|KARP1|KU80|KUB2|Ku86|NFIV
Reference Data
Protein Families Stem cell - Pluripotency, Druggable Genome
Protein Pathways Non-homologous end-joining
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