RGS13 Rabbit Polyclonal Antibody

CAT#: TA308693

Rabbit polyclonal antibody to RGS13 (regulator of G-protein signaling 13)

Product Images

Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. TA308693 diluted at 1:1000.

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  Immunofluorescence analysis of paraformaldehyde-fixed A549, using RGS13 (TA308693) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Mouse, Cow)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 159 of RGS13 (Uniprot ID#O14921)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 19 kDa
• Gene Name: regulator of G-protein signaling 13
• Database Link:
  NP_002918
  Entrez Gene 246709 MouseEntrez Gene 6003 Human
  UniProt ID O14921
• Background: The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq]
• Synonyms: MGC17173
• Note: Seq homology of immunogen across species: mouse (84%), cow (89%)

Reference Data

• Protein Families: Druggable Genome