AKAP10 Rabbit Polyclonal Antibody

SKU TA308653

Rabbit polyclonal antibody to AKAP10 (A kinase (PRKA) anchor protein 10)

Product Data

• Application: IF, IHC
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000
• Reactivity: Human (Predicted: Mouse, Rat)
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 600 and 662 of AKAP10 (Uniprot ID#O43572)
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 74 kDa
• Gene Name: A-kinase anchoring protein 10
• Database Link:
  NP_009133
  O43572
• Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction. [provided by RefSeq]
• Synonyms: AKAP-10; D-AKAP-2; D-AKAP2; PRKA10
• Note: Seq homology of immunogen across species: Mouse (85%), Rat (85%)

Reference Data

• Protein Families: Druggable Genome