Kallikrein 7(KLK7) Rabbit Polyclonal Antibody
Rabbit polyclonal antibody to KLK7 (kallikrein-related peptidase 7)
Product Datasheet for 'TA308502'
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|Recommend Dilution||IHC:1:100-1:1000; WB:1:1000-1:10000|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 253 of KLK7 (Uniprot ID#P49862)|
|Formulation||0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purification||Purified by antigen-affinity chromatography.|
|Predicted Protein Size||28kDa|
|Gene Name||kallikrein related peptidase 7|
|Background||Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq]|
|Protein Families||Secreted Protein, Druggable Genome|