NDUFS4 Rabbit Polyclonal Antibody

CAT#: TA308443

Rabbit Polyclonal antibody to NDUFS4 (NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase))

Product Images

Sample (50 ug of whole cell lysate). A: Mouse brain. 12% SDS PAGE. TA308443 diluted at 1:1000.

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  NDUFS4 antibody detects NDUFS4 protein by Western blot analysis. A. 50 ug Rat heart lysate/extract. 12% SDS-PAGE. NDUFS4 antibody (TA308443) dilution: 1:1000.

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  Sample (30ug whole cell lysate). A: 293T. 12% SDS PAGE. TA308443 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded OVCA, using NDUFS4 (TA308443) antibody at 1:100 dilution.

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  Immunofluorescence analysis of methanol-fixed HeLa, using NDUFS4 (TA308443) antibody at 1:100 dilution.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 175 of NDUFS4 (Uniprot ID#O43181)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20 kDa
• Gene Name: NADH:ubiquinone oxidoreductase subunit S4
• Database Link:
  NP_002486
  Entrez Gene 17993 MouseEntrez Gene 4724 Human
  UniProt ID O43181
• Background: This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq]
• Synonyms: AQDQ; CI-18

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease