KAT2B Rabbit Polyclonal Antibody

CAT#: TA308325

Rabbit Polyclonal antibody to PCAF (K(lysine) acetyltransferase 2B)

Product Images

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308325 diluted at 1:1000.

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  Sample (30 ug whole cell lysate). A:Hep G2. 7.5% SDS PAGE. TA308325 diluted at 1:1000

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human, Mouse (Predicted: Zebrafish)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 767 and 832 of PCAF (Uniprot ID#Q92831)
• Formulation: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 93 kDa
• Gene Name: lysine acetyltransferase 2B
• Database Link:
  NP_003875
  Entrez Gene 18519 MouseEntrez Gene 8850 Human
  UniProt ID Q92831
• Background: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq]
• Synonyms: CAF; P; PCAF
• Note: Seq homology of immunogen across species: Zebrafish (88%)

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Notch signaling pathway