RASAL1 Rabbit Polyclonal Antibody

CAT#: TA308003

Rabbit polyclonal antibody to RASAL1 (RAS protein activator like 1 (GAP1 like))

Product Images

Sample (30 ug of whole cell lysate). A: A431. 7.5% SDS PAGE. TA308003 diluted at 1:1000

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  Immunofluorescence analysis of paraformaldehyde-fixed A549, using RASAL1 (TA308003) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Rat)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 516 and 787 of RASAL1 (Uniprot ID#O95294)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 90 kDa
• Gene Name: RAS protein activator like 1
• Database Link:
  NP_004649
  Entrez Gene 360814 RatEntrez Gene 8437 Human
  UniProt ID O95294
• Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. [provided by RefSeq]
• Synonyms: RASAL
• Note: Seq homology of immunogen across species: Rat (86%)