NDUFS2 Rabbit Polyclonal Antibody
CAT#: TA307995
Rabbit Polyclonal antibody to NDUFS2 (NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase))
USD 436.00
USD 867.00
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000 |
Reactivities | Human, Mouse (Predicted: Chimpanzee) |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fragment corresponding to a region within amino acids 200 and 430 of NDUFS2 (Uniprot ID#O75306) |
Formulation | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 53 kDa |
Gene Name | NADH:ubiquinone oxidoreductase core subunit S2 |
Database Link | |
Background | Mitochondrial complex I (NADH-ubiquinone reductase; EC 1.6.5.3) is the first multimeric complex of the respiratory chain that catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mammalian mitochondrial complex I is an assembly of at least 43 different subunits. Seven of the subunits are encoded by the mitochondrial genome; the remainder are the products of nuclear genes. The iron-sulfur protein (IP) fraction of complex I is made up of 7 subunits, including NDUFS2. See NDUFS1 (MIM 157655). [supplied by OMIM] |
Synonyms | CI-49 |
Note | Seq homology of immunogen across species: Chimpanzee (100%) |
Reference Data | |
Protein Pathways | Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
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