ZC3H12B Rabbit Polyclonal Antibody

CAT#: TA306954

Rabbit Polyclonal ZC3H12B Antibody

Product Images

Western blot analysis of ZC3H12B in mouse brain tissue lysate with ZC3H12B antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of ZC3H12B in human brain tissue with ZC3H12B antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ZC3H12B antibody was raised against a 17 amino acid peptide near the amino terminus of human ZC3H12B.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: zinc finger CCCH-type containing 12B
• Database Link:
  NP_001010888
  Entrez Gene 547176 MouseEntrez Gene 296864 RatEntrez Gene 340554 Human
  UniProt ID Q5HYM0
• Background: ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).
• Synonyms: CXorf32; MCPIP2