Angiotensin II Type 2 Receptor (AGTR2) Rabbit Polyclonal Antibody

CAT#: TA306840

Rabbit Polyclonal AGTR2 Antibody

Product Images

Western blot analysis of AGTR2 in mouse liver tissue lysate with AGTR2 antibody at 0.5 ug/ml.

• 

  Immunohistochemistry of AGTR2 in rat liver tissue with AGTR2 antibody at 5 ug/ml.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 0.5 ug/mL, ICC: 5 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: AGTR2 antibody was raised against a 16 amino acid peptide from near the center of human AGTR2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: angiotensin II receptor type 2
• Database Link:
  NP_000677
  Entrez Gene 11609 MouseEntrez Gene 24182 RatEntrez Gene 186 Human
  UniProt ID P50052
• Background: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
• Synonyms: AT2; ATGR2; MRX88

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction, Renin-angiotensin system