TAPA1 (CD81) Rabbit Polyclonal Antibody

CAT#: TA306789

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Rabbit Polyclonal CD81 Antibody



USD 484.00


Availability*
2 Weeks

Size
    • 100 ug


Product images

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen CD81 antibody was raised against a 20 amino acid peptide near the amino terminus of human CD81.
Formulation PBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name CD81 molecule
Background CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.
Synonyms CVID6; S5.7; TAPA1; TSPAN28
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways B cell receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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