Prealbumin (TTR) Chicken Polyclonal Antibody

CAT#: TA306775

Chicken Polyclonal Transthyretin Antibody

Product Images

Western blot analysis of Transthyretin in human lung tissue lysate with Transthyretin antibody at (A) 1 and (B) 2 ug/ml.

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  Immunohistochemistry of Transthyretin in human lung tissue with Transthyretin antibody at 2.5 ug/ml.

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  Immunofluorescence of Transthyretin in human lung tissue with Transthyretin antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Chicken
• Isotype: IgY
• Clonality: Polyclonal
• Immunogen: Transthyretin antibody was raised against a 17 amino acid peptide near the center of human Transthyretin .
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: transthyretin
• Database Link:
  NP_000362
  Entrez Gene 22139 MouseEntrez Gene 24856 RatEntrez Gene 7276 Human
  UniProt ID P02766
• Background: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson’s disease, schizophrenia, and depression.
• Synonyms: CTS; CTS1; HEL111; HsT2651; PALB; TBPA

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Secreted Protein