Orexin Receptor 1(HCRTR1) Goat Polyclonal Antibody
Goat Polyclonal Antibody against HCRTR1
Product Datasheet for 'TA303362'
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|Recommend Dilution||ELISA: 1:32,000. WB: 0.3-1µg/ml.|
|Reactivity||Test: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow|
|Immunogen||Peptide with sequence C-YNFLSGKFREQFK, from the internal region of the protein sequence according to NP_001516.1; NP_001517.1.|
|Formulation||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purification||Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Gene Name||hypocretin receptor 1|
|Background||The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq].|
|Protein Families||GPCR, ES Cell Differentiation/IPS, Transmembrane, Druggable Genome|
|Protein Pathways||Neuroactive ligand-receptor interaction|
|The use of this Antibodies has been cited in the following citations:|
Hypocretin (Orexin) Regulates Glutamate Input to Fast-Spiking Interneurons in Layer V of the Fr2 Region of the Murine Prefrontal Cortex
,Aracri, P;Banfi, D;Pasini, ME;Amadeo, A;Becchetti, A;,
Cereb. Cortex Dec 2013.
,PubMed ID 24297328
[Mouse; WB & IF]