PTF1A Goat Polyclonal Antibody

CAT#: TA303246

Goat Polyclonal Antibody against PTF1A

Product Images

TA303246 (0.5ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:32,000. WB: 0.5-1.5µg/ml.
• Reactivities: Human, Mouse (Expected from sequence similarity: Rat, Dog, Zebrafish)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-WTDEKQLKEQN, from the internal region of the protein sequence according to NP_835455.1.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: pancreas specific transcription factor, 1a
• Database Link:
  NP_835455
  Entrez Gene 19213 MouseEntrez Gene 117034 RatEntrez Gene 608313 DogEntrez Gene 256297 Human
  UniProt ID Q7RTS3
• Background: This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq]
• Synonyms: bHLHa29; PACA; PAGEN2; PTF1-p48

Reference Data

• Protein Families: Embryonic stem cells, ES Cell Differentiation/IPS