Leptin Receptor (LEPR) Goat Polyclonal Antibody

SKU TA302673

Goat Polyclonal Antibody against Leptin Receptor

Product Data

• Application: FC, IHC, PEP-ELISA, WB
• Recommended Dilution: ELISA: 1:16,000. WB: 1-3µg/ml.IHC:4µg/ml
• Reactivity: Human (Expected from sequence similarity: Dog)
• Antibody Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-TQDDIEKHQSDAG, from the internal region of the protein sequence according to NP_002294.2; NP_001003679.1; NP_001003680.1.
• Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 132.3 kDa
• Gene Name: leptin receptor
• Database Link:
  NP_002294
  P48357
• Background: Leptin (LEP; MIM 164160), an adipocyte-specific hormone that regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure, acts through the leptin receptor (LEPR), a single-transmembrane-domain receptor of the cytokine receptor family. [supplied by OMIM]
• Synonyms: CD295; LEP-R; LEPRD; OB-R; OBR

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction