Glucose Transporter GLUT1 (SLC2A1) Rabbit Polyclonal Antibody

USD 490.00


Availability*
2 Weeks

Size
    • 100 ul


Product images

Specifications

Product Data
Applications IF, WB
Recommended Dilution WB: 0.5-2 ug/ml
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide made to an N-terminal region of the human GLUT1 protein (between residues 1-100). [Swiss-Prot #P11166]
Formulation Tris-glycine, 150mM NaCl and 0.05% sodium azide
Purification Immunogen affinity purified
Gene Name solute carrier family 2 member 1
Background Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are seven types of glucose transport carrier proteins, designated as Glut 1 to 7. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes, as in blood brain barrier and blood testis barriers. GLUT1 is a major glucose transporter in the mammalian blood brain barrier. It is ubiquitous, and is present at high levels in primate erythrocytes and brain endothelial cells.
Synonyms CSE; DYT9; DYT17; DYT18; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Adipocytokine signaling pathway, Pathways in cancer, Renal cell carcinoma

Citations (2)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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