Glucose Transporter GLUT1 (SLC2A1) Rabbit Polyclonal Antibody

SKU TA301678

Rabbit Polyclonal Antibody against GLUT1

Product Data

• Application: ChIP, FC, ICC/IF, IHC, WB
• Recommended Dilution: Chromatin Immunoprecipitation, Flow Cytometry: 1 ug/ml, Immunohistochemistry-Frozen: 1:200, Western Blot: 1:500, Flow (Intracellular): 1 ug/ml, Immunohistochemistry: 1:200, In vitro assay, Immunocytochemistry/ Immunofluorescence: 1:1000, Immunohistochemistry-Paraffin: 1:200
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to an N-terminal region of the human GLUT1 protein (between residues 1-100). [Swiss-Prot #P11166]
• Buffer: Tris-glycine, 150mM NaCl and 0.05% sodium azide
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: solute carrier family 2 member 1
• Database Link:
  NP_006507
  P11166
• Background: Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are seven types of glucose transport carrier proteins, designated as Glut 1 to 7. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes, as in blood brain barrier and blood testis barriers. GLUT1 is a major glucose transporter in the mammalian blood brain barrier. It is ubiquitous, and is present at high levels in primate erythrocytes and brain endothelial cells.
• Synonyms: CSE; DYT9; DYT17; DYT18; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Pathways in cancer, Renal cell carcinoma