CYP46 (CYP46A1) Rabbit Polyclonal Antibody

SKU TA301675

Rabbit Polyclonal Antibody against Cyp-46

Product Data

• Application: ICC/IF, IHC, WB
• Recommended Dilution: Western Blot: 1:1000, Immunohistochemistry-Paraffin: 1:200, Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence: 1:500
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to residues between 200-250 of human Cyp46.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: cytochrome P450 family 46 subfamily A member 1
• Database Link:
  NP_006659
  Q9Y6A2
• Background: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum proein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol.
• Synonyms: CP46; CYP46

Reference Data

• Protein Families: Druggable Genome, P450
• Protein Pathways: Primary bile acid biosynthesis