ROBO4 Rabbit Polyclonal Antibody

SKU TA301644

Rabbit Polyclonal Antibody against ROBO4 - Tumor Endothelial Marker

Product Data

• Application: ICC/IF, IHC, WB
• Recommended Dilution: Immunocytochemistry/ Immunofluorescence, Immunohistochemistry: 5 ug/ml, Western Blot: 1:500, Immunohistochemistry-Paraffin: 5 ug/ml
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to a C-terminal region of the human protein (within residues 900-1007). [Swiss-Prot# Q8WZ75]
• Buffer: Tris-citrate/phosphate [pH 7-8] and 0.1% sodium azide
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: roundabout guidance receptor 4
• Database Link:
  NP_061928
  Q8WZ75
• Background: Roundabouts (ROBO) are cell-surface receptors that mediate repulsive signaling mechanisms at the central nervous system midline. However, ROBOs may also mediate attraction mechanisms in the context of vascular development. ROBO4 is a novel roundabout protein which is restricted in expression to endothelial cells in vitro and sites of angiogenesis in vivo. Because it is not expressed on normal endothelial cells, in vivo, it is a promising tumor endothelial marker.
• Synonyms: ECSM4; MRB

Reference Data

• Protein Families: Druggable Genome