Telomerase reverse transcriptase (TERT) Mouse Monoclonal Antibody [Clone ID: 2C4]
SKU
TA301588
Mouse Monoclonal Antibody against Telomerase reverse transcriptase (2C4) - Embryonic Stem Cell Marker
Product Data | |
Clone Name | 2C4 |
---|---|
Application | ChIP, FC, ICC/IF, IHC, IP, WB |
Recommended Dilution | Flow Cytometry: 1:50 - 1:200, Western Blot: 1:500, Immunoprecipitation: 1:10-1:500, Immunocytochemistry/ Immunofluorescence: 1:50-1:200, Chromatin Immunoprecipitation, Immunohistochemistry: 1:50, Immunohistochemistry-Paraffin: 1:50, Chromatin Immunoprecipitation (ChIP) |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgM |
Clonality | Monoclonal |
Immunogen | Full-length recombinant hTERT from insect cells. |
Buffer | PBS with 0.02% Sodium Azide |
Purification | Ascites |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | telomerase reverse transcriptase |
Database Link | |
Background | Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. Telomerase is an enzyme uniquely associated with immortal cell lines and is useful for identifying undifferentiated PSCs. |
Synonyms | CMM9; DKCA2; DKCB4; EST2; hEST2; hTRT; PFBMFT1; TCS1; TP2; TRT |
Reference Data | |
Protein Families | Druggable Genome |
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