HNRPM(HNRNPM) Mouse Monoclonal Antibody [Clone ID: 2A6]

CAT#: TA301557

Mouse Monoclonal Antibody against Heterogenous Nuclear ribonucleoproteins M3/4 (2A6)

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 Product Datasheet for 'TA301557'

USD 393


Availability*
2 Weeks

Size
    • 100 ul

Product images

Specifications

Product Data
Clone Name 2A6
Applications WB, IHC
Recommend Dilution WB: 1: 1000-1: 10,000
Reactivity human, mouse, rat, bovine, porcine, rabbit
Host Mouse
Clonality Monoclonal
Immunogen M19 fusion protein containing full-length human protein.
Isotype IgG2b kappa
Formulation Ascitic fluid and sodium azide
Purification Ascites
Gene Name heterogeneous nuclear ribonucleoprotein M
Background Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogenous nuclear ribonucleoproteins (hnRNPs), play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. A group of abundant hnRNPs, the M1-M4 proteins, appear as a cluster of four proteins. The M proteins are pre-mRNA binding proteins in vivo, and they bind avidly to poly (G) and poly (U) RNA homopolymers in vitro. M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins with greatest similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. The M proteins also possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif) that resembles a repeat in the 64kDa subunit of cleavage stimulation factor, which is involved in 3'-end maturation of pre-mRNAs. Proteins immunologically related to M exist in divergent eukaryotes ranging from human to yeast.
Synonyms CEAR|HNRNPM4|HNRPM|HNRPM4|HTGR1|NAGR1|hnRNP M
Reference Data
Protein Families Druggable Genome
Protein Pathways Spliceosome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations