FE65 (APBB1) Rabbit Polyclonal Antibody
USD 436.00
USD 200.00
USD 867.00
Specifications
Product Data | |
Applications | IP, WB |
Recommended Dilution | Immunoprecipitation: 2-10 ug, Western Blot: 1:1000 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant rat protein expressed in bacteria. |
Formulation | PBS, 15% glycerol and 0.02% sodium azide |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | amyloid beta precursor protein binding family B member 1 |
Database Link | |
Background | FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients. |
Synonyms | FE65; MGC:9072; RIR |
Reference Data | |
Protein Families | Transcription Factors |
Protein Pathways | Alzheimer's disease |
Documents
Product Manuals |
FAQs |
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