FE65 (APBB1) Rabbit Polyclonal Antibody

SKU TA301423

Rabbit Polyclonal Antibody against Fe65

Product Data

• Application: IP, WB
• Recommended Dilution: Immunoprecipitation: 2-10 ug, Western Blot: 1:1000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant rat protein expressed in bacteria.
• Buffer: PBS, 15% glycerol and 0.02% sodium azide
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: amyloid beta precursor protein binding family B member 1
• Database Link:
  NP_001155
  O00213
• Background: FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients.
• Synonyms: FE65; MGC:9072; RIR

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Alzheimer's disease