TLR7 (451-500) Mouse Monoclonal Antibody [Clone ID: 4F4]

SKU SM6026

TLR7 (451-500) mouse monoclonal antibody, clone 4F4, Purified

Product Data

• Clone Name: 4F4
• Application: ELISA, FC, IF, WB
• Recommended Dilution: ELISA.; Immunocytochemistry / Immunofluorescence.; Flow cytometry.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human TLR7 (451-500 aa) purified from E. coli
• Specificity: The antibody recognizes TLR7 at aa 451-500.
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: toll like receptor 7
• Database Link:
  Q9NYK1
• Background: TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors.; Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7,8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.
• Synonyms: Toll-like receptor 7

Reference Data