MHC Class I (monomorphic) Mouse Monoclonal Antibody [Clone ID: CVS22]

SKU SM504F

MHC Class I (monomorphic) mouse monoclonal antibody, clone CVS22, FITC, Purified

Product Data

• Clone Name: CVS22
• Application: FC
• Recommended Dilution: Flow cytometry: Neat-1/10, use 10µl of this working dilution to label 10e6 cells in 100µl.
• Reactivity: Equine
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Equine leucocytes
• Specificity: All tissues
• Buffer: PBS containing 0.09% Sodium azide and 1% BSA; Label: FITC; State: Purified; State: Liquid purified IgG; Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; This product is photosensitive and should be protected from light.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Background: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
• Synonyms: MHC Class 1, HLA Class 1

Reference Data