CD9 Mouse Monoclonal Antibody [Clone ID: MEM-61]

CAT#: SM3039F

CD9 mouse monoclonal antibody, clone MEM-61, FITC

Product Images

Surface staining of NALM-6 human pre-B cell leukemia cell line with anti-human CD9 (MEM-61) FITC. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: MEM-61
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Pre-B cell line NALM-6
• Specificity: The antibody recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa single transmembrane polypeptide expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
• Formulation: Phosphate buffered saline (PBS) containing 15 mM sodium azide
  Label: FITC
  State: Liquid purified Ig fraction
  Label: Conjugated with Fluorescein isothiocyanate under optimum conditions.
  The reagent is free of unconjugated and adjusted for direct use.
• Conjugation: FITC
• Storage: Store the antibody at 2-8°C. Do Not Freeze! This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD9 molecule
• Database Link:
  Entrez Gene 928 Human
  UniProt ID P21926
• Background: CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.
• Synonyms: MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen